Although we would love to think that all of our patients take all of their medications all the time, we know that is not true. In the study that we did at the John Theurer Cancer Center, we found that up to 25% of our patients had admitted that they had not taken all of their medication during the prior month. Why is this important? Investigators in London showed that missing three pills per month, that is 10%, decreased the ability of patients to get into a deep molecular remission. So we want to emphasize to our patients to take their medications, and when we see a patient is failing, one of the first question we want to ask is, “Are you taking your medications?” We do that before we start expensive genetic mutation studies.For more information on managing your patients with CML, and to participate in an interactive case study in which you’ll be able to make clinical decisions for a patient with CP-CML, please view the activity available here.