|Management of Accelerated Phase CML Patient
This case is a 62-year-old female who presented to the local ER with a recent history of left upper side abdominal pain, poor appetite, night sweats and a 20 lb. weight loss over the past two months.
|Newly Diagnosed CML – Addressing Primary Resistance
This case is a 57-year-old male who presented to the local ER with left side upper quadrant abdominal pain, poor appetite, night sweats and recent weight loss of 20 pounds.
|Newly Diagnosed CML
Our patient is a 27-year-old male who presents with fatigue, early satiety, and right upper quadrant pain. He has no prior medical history.
|Strategies in the Management of Secondary Resistance and in Chronic Phase CML
This is the case of the patient with secondary resistance to imatinib. The patient is a 24-year-old previously healthy African American woman who initially presented in June 2007 with a 2-month history of headaches and weight loss.
|Management of the Blast Crisis CML Patient
The patient is a 57-year-old Caucasian woman in whom the diagnosis of chronic myeloid leukemia was established in July 2008 when during routine physical examination, she was noted to have a white blood cell count of 98. A bone marrow examination revealed chromosome translocation 9;22 in 100% of the metaphases. Her past medical history was notable for hepatitis C infection due to blood transfusion that was successfully treated with Interferon and ribavirin. The patient began treatment with imatinib 400 mg orally daily and 6 months after the initiation of treatment in January 2009 had achieved a complete cytogenetic response.